Research Article

The Impact of Normalization Methods on RNA-Seq Data Analysis

Table 3

Rank of the bias values obtained using five normalization methods and RD for the normalization of the three tested data sets.

Normalization methodCheung data set rank (bias value)Bodymap data set rank (bias value)AML data set rank (bias value)

TMM3.5 (0.890)4 (1.123)6 (0.587)
UQ3.5 (0.890)5 (1.139)4 (0.564)
DES1 (0.885)2 (1.102)1 (0.512)
EBS2 (0.887)3 (1.111)3 (0.532)
PS5 (0.893)1 (1.098)2 (0.523)
RD6 (0.908)6 (1.159)5 (0.581)