Research Article

The Impact of Normalization Methods on RNA-Seq Data Analysis

Table 4

Rank of the variance values obtained using the five normalization methods and RD for the normalization of the three tested data sets.

Normalization methodCheung data set rank (variance value)Bodymap data set rank (variance value)AML data set rank (variance value)

TMM4 (0.779)4 (1.305)6 (0.364)
UQ3 (0.778)5 (1.330)4 (0.335)
DES1 (0.768)2 (1.270)1 (0.283)
EBS2 (0.771)3 (1.283)3 (0.300)
PS5 (0.782)1 (1.268)2 (0.291)
RD6 (0.812)6 (1.390)5 (0.355)