The Impact of Normalization Methods on RNA-Seq Data Analysis

Table 5

Sensitivity and specificity of the studied five normalization methods and RD applied to the AML data set.

Methods	TMM	UQ	DES	EBS	PS	RD
Sensitivity (%)	11.4	20.5	18.2	45.5	40.9	18.2
Rank of sensitivity	6	3	4.5	1	2	4.5
Specificity (%)	97.7	84.1	97.7	52.3	65.9	97.7
Rank of specificity	2	4	2	6	5	2