Mining for Candidate Genes Related to Pancreatic Cancer Using Protein-Protein Interactions and a Shortest Path Approach

Table 1

Detailed information on the thirteen candidate genes.

Row number	Ensembl ID	Gene symbol	Full name	Betweenness	Permutation FDR
1	ENSP00000216797	NFKBIA	Nuclear Factor of Kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, Alpha	73	0.002
2	ENSP00000269321	ARHGDIA	Rho GDP Dissociation Inhibitor (GDI) Alpha	94	0.012
3	ENSP00000347858	XIAP	X-Linked Inhibitor of Apoptosis, E3 Ubiquitin Protein Ligase	64	0.006
4	ENSP00000250894	MAPK8IP3	Mitogen-Activated Protein Kinase 8 Interacting Protein 3	64	<0.001
5	ENSP00000262613	SLC9A3R1	Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1	128	0.031
6	ENSP00000384515	PARVB	Parvin, Beta	64	<0.001
7	ENSP00000254066	RARA	Retinoic Acid Receptor, Alpha	24	0.005
8	ENSP00000299421	ILK1	Integrin-linked kinase 1	64	0.03
9	ENSP00000338934	EZR	Ezrin	128	0.026
10	ENSP00000309845	HRAS	Harvey Rat Sarcoma Viral Oncogene Homolog	113	0.033
11	ENSP00000335153	HSP90AA1	Heat Shock Protein 90 kDa Alpha (Cytosolic), Class A Member 1	230	0.007
12	ENSP00000348986	INS-IGF2	INS-IGF2 Readthrough	64	0.031
13	ENSP00000284384	PRKCA	Protein Kinase C, Alpha	175	<0.001