Research Article
Mining for Candidate Genes Related to Pancreatic Cancer Using Protein-Protein Interactions and a Shortest Path Approach
Table 1
Detailed information on the thirteen candidate genes.
| Row number | Ensembl ID | Gene symbol | Full name | Betweenness | Permutation FDR |
| 1 | ENSP00000216797 | NFKBIA | Nuclear Factor of Kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, Alpha | 73 | 0.002 | 2 | ENSP00000269321 | ARHGDIA | Rho GDP Dissociation Inhibitor (GDI) Alpha | 94 | 0.012 | 3 | ENSP00000347858 | XIAP | X-Linked Inhibitor of Apoptosis, E3 Ubiquitin Protein Ligase | 64 | 0.006 | 4 | ENSP00000250894 | MAPK8IP3 | Mitogen-Activated Protein Kinase 8 Interacting Protein 3 | 64 | <0.001 | 5 | ENSP00000262613 | SLC9A3R1 | Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 | 128 | 0.031 | 6 | ENSP00000384515 | PARVB | Parvin, Beta | 64 | <0.001 | 7 | ENSP00000254066 | RARA | Retinoic Acid Receptor, Alpha | 24 | 0.005 | 8 | ENSP00000299421 | ILK1 | Integrin-linked kinase 1 | 64 | 0.03 | 9 | ENSP00000338934 | EZR | Ezrin | 128 | 0.026 | 10 | ENSP00000309845 | HRAS | Harvey Rat Sarcoma Viral Oncogene Homolog | 113 | 0.033 | 11 | ENSP00000335153 | HSP90AA1 | Heat Shock Protein 90 kDa Alpha (Cytosolic), Class A Member 1 | 230 | 0.007 | 12 | ENSP00000348986 | INS-IGF2 | INS-IGF2 Readthrough | 64 | 0.031 | 13 | ENSP00000284384 | PRKCA | Protein Kinase C, Alpha | 175 | <0.001 |
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