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BioMed Research International
Volume 2015, Article ID 623986, 11 pages
http://dx.doi.org/10.1155/2015/623986
Research Article

Evolution of Coronary Flow in an Experimental Slow Flow Model in Swines: Angiographic and Pathological Insights

Department of Cardiology, Wuhan Puai Hospital, Huazhong University of Science and Technology, Wuhan 430030, China

Received 1 July 2015; Revised 6 August 2015; Accepted 9 August 2015

Academic Editor: Kai Hu

Copyright © 2015 Yupeng Bai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The short description (in paragraph style) of the Supplementary Material:

The measurement of TIMI flow grade and the TFC (TIMI flow count) was acquired by two experienced technicians. Each frame was recorded and analyzed by TOSHIBA Infinix cardiovascular interventional imaging system. Film speed was 30 frames per second. The following three criteria were used to define the first frame: (1) Contrast agent reached initiating terminal of the arteries; (2) Contrast agents contacted the two sides of initiating terminal of the artery; (3) Evidence of forward movement of the contrast agent. The last frame was counted when the contrast agent reached to the farthest portion of the branch, but there is no need to fulfill the branch. Anatomical marks: the farthest branch of anterior descending branch (LAD) was defined by the tail of the whale or grass fork imaging sign.

video 1: Representative CAG imagines showing TFC at baseline in a pig from SF-28D group (TIMI grade=3, TFC=15, corresponding Figure 1A).

video 2: Representative CAG imagines showing TFC immediately at the time of slow flow formation in a pig from SF-28D group (Coronary flow in LAD was very slow, TIMI grade=2, TFC=60, corresponding Figure 1B).

video 3: Representative CAG imagines showing TFC at 5min post slow flow formation in a pig from SF-28D group (Coronary flow in LAD presented fast recovery, TIMI grade=2, TFC=43, corresponding Figure 1C).

video 4: Representative CAG imagines showing TFC at 15min post slow flow formation in a pig from SF-28D group (Coronary flow in LAD presented slow recovery, TIMI grade=2, TFC=38, corresponding Figure 1D).

video 5: Representative CAG imagines showing TFC at 30min post slow flow formation in a pig from SF-28D group (Coronary flow in LAD presented slow recovery, TIMI grade=2, TFC=36, corresponding Figure 1E).

video 6: Representative CAG imagines showing TFC at 1 hour post slow flow formation in a pig from SF-28D group (Coronary flow in LAD presented slow recovery, TIMI grade=2, TFC=35, corresponding Figure 1F).

video 7: Representative CAG imagines showing TFC at 3 hours post slow flow formation in pig from SF-28D group (Coronary flow in LAD presented slow recovery, TIMI grade=2, TFC=29 , corresponding Figure 1G).

video 8: Representative CAG imagines showing TFC at 7 days post slow flow formation in a pig from SF-28D group (Coronary flow in LAD presented plateau period, TIMI grade=2, TFC=28, corresponding Figure 1H)

video 9: Representative CAG imagines showing TFC at 28 days post slow flow formation in a pig from SF-28D group (Coronary flow in LAD returned to baseline level, TIMI grade=3, TFC=16, corresponding Figure 1I).

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