Evolution of Coronary Flow in an Experimental Slow Flow Model in Swines: Angiographic and Pathological Insights
Table 2
Angiographic and hemodynamic parameters at baseline, 3 hours, 7 days, and 28 days after LAD coronary microspheres injection.
Group
Variable
Time points
Baseline
3 hours
7 days
28 days
CON ()
HR (beats/min)
133 ± 13
122 ± 15
131 ± 8
129 ± 9
TIMI (grade)
3 ± 0
3 ± 0
3 ± 0
3 ± 0
TMPG (grade)
3 ± 0
3 ± 0
3 ± 0
3 ± 0
TFC (frame)
15.8 ± 3.4
15.8 ± 1.7
16.2 ± 2.2
16.0 ± 2.4
LVSP (mmHg)
150.6 ± 12.3
145.3 ± 15.8
147.8 ± 10.2
146.8 ± 8.2
LVEDP (mmHg)
7.9 ± 2.4
8.6 ± 1.9
7.7 ± 2.4
7.7 ± 2.3
LVEDV (mL)
24.0 ± 3.5
24.1 ± 3.6
24.8 ± 4.0
28.9 ± 4.2
LVESV (mL)
7.7 ± 1.3
7.9 ± 1.4
8.2 ± 1.7
9.9 ± 1.5
LVEF (%)
67.5 ± 3.8
66.8 ± 3.4
66.7 ± 3.9
65.4 ± 4.5
SF-28D ()
HR (beats/min)
129 ± 11
110 ± 7
127 ± 7.3
124 ± 6
TIMI (grade)
3 ± 0
2 ± 0
2 ± 0
3 ± 0
TMPG (grade)
3 ± 0
0.3 ± 0.5
0.8 ± 0.4
3 ± 0
TFC (frame)
16.2 ± 4.2
31.5 ± 11.7
30.6 ± 12.2
17.4 ± 2.7
LVSP (mmHg)
146.8 ± 15.3
112.5 ± 10.3
122 ± 8.2
123.6 ± 8.9
LVEDP (mmHg)
7.7 ± 3.7
15.0 ± 2.1
14.4 ± 1.5
14.3 ± 1.2
LVEDV (mL)
24.5 ± 3.4
25.5 ± 3.7
28.7 ± 3.1
33.0 ± 3.8
LVESV (mL)
7.7 ± 1.5
11.7 ± 2.6
13.2 ± 2.5
13.9 ± 3.1
LVEF (%)
68 ± 5
55 ± 5
54 ± 8
58 ± 6
TIMI: thrombolysis in myocardial infarction, TMPG: TIMI myocardial perfusion grade, TFC: TIMI frame count, LVSP: LV systolic pressure, LVEDP: LV end-diastolic pressure, LVEDV: LV end-diastolic volume, LVESV (mL): LV end-systolic volume, and LVEF: LV ejection fraction. All the data showed with mean ± standard deviation. versus baseline, versus CON group.
