Monitoring the Modifications of the Vitreous Humor Metabolite Profile after Death: An Animal Model

Figure 1

Aliphatic region (0.8–4.3 ppm) of the ¹H NMR spectra of VH samples withdrawn at different times after death (0 and 6, 12, 18, and 24 hours). The region 1.30–1.36 ppm, due to the disproportionate intensity of the lactate doublet, is not shown. Major assignments are reported. Branched chain amino acids (BCAA: isoleucine, leucine, and valine), 3-hydroxybutyrate (3-OH-But), alanine (Ala), acetate (Ace), glutamate (Glu), glutamine (Gln), glutathione in its reduced and oxidized forms (GSH/GSSG), creatine (Crt), choline/phosphocholine (Cho), taurine (Tau), glucose (Gluc), betaine (Bet), myo-inositol (MI), ascorbate (Asc), and lactate (Lac).