Monitoring the Modifications of the Vitreous Humor Metabolite Profile after Death: An Animal Model

Figure 4

Concentration %, with respect to the t0 samples, versus time of (a) glucose (Gluc), myo-inositol (MI), creatine (Crt), alanine (Ala), 3-hydroxybutyrate (3-OH-But), choline/phosphocholine (Cho), and lactate (Lac); (b) glutathione, in its reduced and oxidized forms (GSH/GSSG), and hypoxanthine (Hpx). Chemical shift range (ppm) of the corresponding integrated areas in the ¹H NMR spectra: Gluc 3.46–3.48, MI 4.06–4.08, Crt 3.92–3.94, Ala 1.46–1.48, 3-OH-But 1.20–1.22, Cho 3.20–3.22, Lac 1.34–1.36, GSH/GSSG 2.96–2.98, and Hpx 8.20–8.22.

(a)

(b)