Dexamethasone Enhanced Functional Recovery after Sciatic Nerve Crush Injury in Rats

Figure 5

Histological analysis by H&E staining of rat sciatic nerves on day 28 after surgery. (n) Sciatic nerve on nonoperated side. Group (a) (sham) shows well-organized myelin sheets, round axons, and absence of infiltrating cells. Group (b) shows several areas of edema and degraded myelin sheets (black arrow) and several infiltrating mononuclear cells. Groups (c)–(e) show effects of dexamethasone on the injured sciatic nerves. The red arrow shows that alleviated areas of edema and nerve fibers seem to be better organized than those in group (b). Magnification, ×400.