Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2015 (2015), Article ID 627923, 9 pages
http://dx.doi.org/10.1155/2015/627923
Research Article

Dexamethasone Enhanced Functional Recovery after Sciatic Nerve Crush Injury in Rats

1Department of Neurology, Beijing Tsinghua Changgung Hospital, Medical Center, Tsinghua University, No. 168 Li Tang Road, Changping District, Beijing 102218, China
2Department of Spine Surgery, Aviation General Hospital of China Medical University, Beijing Institute of Translational Medicine, Chinese Academy of Sciences, No. 3 Anwai Beiyuan Road, Chaoyang District, Beijing 100012, China

Received 30 November 2014; Accepted 6 January 2015

Academic Editor: Kirsten Haastert-Talini

Copyright © 2015 Xinhong Feng and Wei Yuan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T.-H. Kim, S.-J. Yoon, W.-C. Lee et al., “Protective effect of GCSB-5, an herbal preparation, against peripheral nerve injury in rats,” Journal of Ethnopharmacology, vol. 136, no. 2, pp. 297–304, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. M. G. Burnett and E. L. Zager, “Pathophysiology of peripheral nerve injury: a brief review,” Neurosurg Focus, vol. 16, article E1, 2004. View at Google Scholar · View at Scopus
  3. L. Steinman, “Elaborate interactions between the immune and nervous systems,” Nature Immunology, vol. 5, no. 6, pp. 575–581, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. L. R. Watkins, M. R. Hutchinson, E. D. Milligan, and S. F. Maier, “‘Listening’ and ‘talking’ to neurons: implications of immune activation for pain control and increasing the efficacy of opioids,” Brain Research Reviews, vol. 56, no. 1, pp. 148–169, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. E. A. A. Salegio, A. N. Pollard, M. Smith, and X.-F. Zhou, “Sciatic nerve conditioning lesion increases macrophage response but it does not promote the regeneration of injured optic nerves,” Brain Research, vol. 1361, pp. 12–22, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. A. M. Xavier, K. G. G. Serafim, D. T. Higashi et al., “Simvastatin improves morphological and functional recovery of sciatic nerve injury in Wistar rats,” Injury, vol. 43, no. 3, pp. 284–289, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. A. H. Koeppen, “Wallerian degeneration: history and clinical significance,” Journal of the Neurological Sciences, vol. 220, no. 1-2, pp. 115–117, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. D. W. Zochodne, “The microenvironment of injured and regenerating peripheral nerves,” Muscle & Nerve Supplements, vol. 9, pp. S33–s38, 2000. View at Google Scholar · View at Scopus
  9. H. Sun, T. Yang, Q. Li et al., “Dexamethasone and vitamin B12 synergistically promote peripheral nerve regeneration in rats by upregulating the expression of brain-derived neurotrophic factor,” Archives of Medical Science, vol. 8, no. 5, pp. 924–930, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. R. Mohammadi, M. Azad-Tirgan, and K. Amini, “Dexamethasone topically accelerates peripheral nerve repair and target organ reinnervation: a transected sciatic nerve model in rat,” Injury, vol. 44, no. 4, pp. 565–569, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. J. R. Bain, S. E. Mackinnon, and D. A. Hunter, “Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat,” Plastic and Reconstructive Surgery, vol. 83, no. 1, pp. 129–138, 1989. View at Publisher · View at Google Scholar · View at Scopus
  12. S. Canan, H. H. Bozkurt, M. Acar et al., “An efficient stereological sampling approach for quantitative assessment of nerve regeneration,” Neuropathology and Applied Neurobiology, vol. 34, no. 6, pp. 638–649, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. I. Allodi, E. Udina, and X. Navarro, “Specificity of peripheral nerve regeneration: interactions at the axon level,” Progress in Neurobiology, vol. 98, no. 1, pp. 16–37, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. P. Dinh, A. Hazel, W. Palispis, S. Suryadevara, and R. Gupta, “Functional assessment after sciatic nerve injury in a rat model,” Microsurgery, vol. 29, no. 8, pp. 644–649, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. Y. Yuan, H. Shen, J. Yao, N. Hu, F. Ding, and X. Gu, “The protective effects of Achyranthes bidentata polypeptides in an experimental model of mouse sciatic nerve crush injury,” Brain Research Bulletin, vol. 81, no. 1, pp. 25–32, 2010. View at Publisher · View at Google Scholar · View at Scopus
  16. G. K. Ha, S. Parikh, Z. Huang, and J. M. Petitto, “Influence of injury severity on the rate and magnitude of the T lymphocyte and neuronal response to facial nerve axotomy,” Journal of Neuroimmunology, vol. 199, no. 1-2, pp. 18–23, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. K. Temporin, H. Tanaka, Y. Kuroda et al., “Interleukin-1 beta promotes sensory nerve regeneration after sciatic nerve injury,” Neuroscience Letters, vol. 440, no. 2, pp. 130–133, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. N. Irwin, S. Chao, L. Goritchenko et al., “Nerve growth factor controls GAP-43 mRNA stability via the phosphoprotein ARPP-19,” Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 19, pp. 12427–12431, 2002. View at Publisher · View at Google Scholar · View at Scopus
  19. L. I. Benowitz and A. Routtenberg, “GAP-43: an intrinsic determinant of neuronal development and plasticity,” Trends in Neurosciences, vol. 20, no. 2, pp. 84–91, 1997. View at Publisher · View at Google Scholar · View at Scopus