Curcumin Enhanced Busulfan-Induced Apoptosis through Downregulating the Expression of Survivin in Leukemia Stem-Like KG1a Cells

Figure 5

Expression of antiapoptosis protein survivin in KG1a cells. (a, b) KG1a cells were treated with CUR (16 μM), BUS (80 μM), or CUR + BUS for 48 h tested by protein arrays kit (a) as described in “methods.” The intensities of green fluorescence spots represent survivin expression. Survivin expression was significantly decreased in CUR and CUR + BUS groups, compared with controls, the same as the results analyzed by western blot analysis.

(a)

(b)