Table 4: Descriptive statistics (mean and standard deviation) for headache diary and migraine specific health related quality of life measures (). Values reported at baseline, week-four, and week-eight for headache diary, HIT-62, and MSQL4,5,6; baseline and week-twelve (week eight after intervention) for the MIDAS7. Baseline and follow-up differences analyzed using the paired -test, described as mean difference and 95% CI1. A score decrease indicates improvement for diary and HIT-62 results. MSQL4,5,6 scores increase with subject HRQoL3 improvement.
(a)

Baseline
mean
(SD)
Week-4
mean
(SD)
Week-8
mean
(SD)
Difference baseline to week-4
mean (95% CI1)
value
Difference baseline to week-8
mean (95% CI1)
value

Headache diary
Headache days per month14.5
(5.7)
11.4
(5.2)
8.7
(4.3)
3.1 (0.19, 6.0)
5.7 (2.0, 9.4)
Headache intensity2.8
(0.96)
2.6
(0.89)
2.1
(1.18)
0.17 (−0.53, 0.86)
0.69 (−0.32, 1.71)

Health Related Quality of Life (HRQoL)
HIT-6264.2
(3.8)
55.3
(7.7)
53.8
(6.8)
8.9 (4.9, 13.0)
10.4 (6.9, 13.8)
MSQL-R638.4
(17.4)
69.1
(22.7)
73.5
(28.0)
30.7 (22.4, 38.9)
35.1 (23.5, 46.6)
MSQL-E453.3
(23.5)
82.4
(16.9)
81.2
(29.2)
29.1 (15.9, 42.3)
27.9(12.9, 43.1)
MSQL-P554.1
(18.1)
83.2
(16.9)
86.8
(16.9)
29.1 (16.8, 41.4)
32.7 (21.3, 44.5)

(b)

Baseline
mean
(SD)
Week-12
mean
(SD)
Difference
mean (95% CI)
value

MIDAS746.7
(27.7)
14.6
(23.8)
32.1 (13.2, 51.0)

CI: confidence interval.
2HIT-6: Headache Impact Test-6.
3HRQoL: Health Related Quality of Life.
4MSQL-E: Migraine-Specific Quality of Life Measure-Emotional.
5MSQL-P: Migraine-Specific Quality of Life Measure-Physical.
6MSQL-R: Migraine-Specific Quality of Life Measure-Restrictive.
7MIDAS: Migraine Disability Assessment Scale.