Vascular Damage in Resistant Hypertension: TNF-Alpha Inhibition Effects on Endothelial Cells

Table 2

General characteristics of normotensive and resistant hypertensive subjects.

	NT; ()	RHTN; ()	value
Age (years)	52 ± 5.0	57 ± 13	0.06
Gender (F/M)	9/10	19/13	0.56
BMI (kg/m^2)	25.1 ± 2.3	26.3 ± 2.9	0.14
Office SBP (mmHg)	121 ± 14	146 ± 16	<0.0001
Office DBP (mmHg)	78 ± 8	86 ± 14	0.04
Office PP (mmHg)	43 ± 9	61 ± 13	<0.0001
PWV (m/s)	7.2 ± 1.0	10.5 ± 2.2	<0.001
TNF- (pg/mL)	2.1 ± 1.2	3.3 ± 3.1	0.04

Mean ± SD. NT: normotensive subjects; RHTN: resistant hypertensive patients; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; PP: pulse pressure; PWV: pulse wave velocity; TNF-α: tumoral necrosis factor-α. versus NT.