Breast Cancer-Derived Extracellular Vesicles: Characterization and Contribution to the Metastatic Phenotype

Table 1

Comparison of breast cancer-derived MV and exosomal proteins.

Role	Microvesicles	Exosomes
Extracellular matrix degradation	EMPRINN [42, 78]; ARF1 [144]	ADAM10 [51, 65]
Cancer invasion/metastasis	RhoA/RhoC GTPase [144]; FAK [41]; EGFR [41]; TF [53, 54, 147]	Annexins A2, A5, and A6 [55, 56, 97, 98]; EpCAM [57, 65, 120]; H2A [46]; CD24 [65]; HSP70 [36, 65]; α-enolase [57]; Integrins α3, α6 [56]
Cell survival	IDO [128]; tTG [107]	PRDX2 [56]; HSC70 [56]