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BioMed Research International
Volume 2015, Article ID 635748, 8 pages
http://dx.doi.org/10.1155/2015/635748
Research Article

MicroRNA and mRNA Features of Malignant Pleural Mesothelioma and Benign Asbestos-Related Pleural Effusion

1Department of Chest Diseases, Medical Faculty, Eskisehir Osmangazi University, 26480 Eskisehir, Turkey
2Division of Thoracic Surgery, Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
3Department of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA
4Division of Oncology, National Jewish Health, Denver, CO 80206, USA
5Department of Public Health, Medical Faculty, Eskisehir Osmangazi University, 26480 Eskisehir, Turkey
6Department of Pathology, Medical Faculty, Eskisehir Osmangazi University, 26480 Eskisehir, Turkey
7Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
8Division of Pulmonary & Critical Care Medicine, Mayo Clinic, Rochester, MN 55905, USA

Received 31 August 2014; Accepted 27 October 2014

Academic Editor: Seiichi Saito

Copyright © 2015 Guntulu Ak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Selected pathways by an integrated analyses of mRNA and miRNA data. Over-expressed genes and targets of under-expressed miRNA in mesothelioma are shown in blue and yellow shading, respectively. Genes in green shading were over-expressed and also targets of under-expressed miRNA. These included a number of prominent cancer genes such as MET and CCNE2.

  1. Supplementary Material