Research Article

Parathyroidectomy Is Associated with Reduced Mortality in Hemodialysis Patients with Secondary Hyperparathyroidism

Table 1

Comparison of baseline characteristics of survivors and nonsurvivors from 221 hemodialysis patients with iPTH over 800 pg/mL.

Survival status value
SurvivalDeath
( = 188)( = 33)

Basic characteristics

Age (year)<65n 13114
%69.7%42.4%
≥65n 5719
%30.3%57.6%
Mean57.5 ± 12.967.6 ± 11.0<0.

SexFemalen 11316
%60.1%48.5%
Malen 7517
%39.9%51.5%

HypertensionNon 6815
%36.2%45.5%
Yesn 12018
%63.8%54.5%

Diabetes mellitusNon 1149<0.
%60.6%27.3%
Yesn 7424
%39.4%72.7%

Duration of dialysis (month)Mean97.6 ± 54.484.9 ± 56.0

Mean1.38 ± 0.241.40 ± 0.20

Biochemical parameters

Hemoglobin (g/dL)<10n 8216
%43.6%48.5%
≥10n 10617
%56.4%51.5%
Mean10.2 ± 1.410.3 ± 1.7

Albumin (g/dL)<3.5n 63
%3.2%9.1%
≥3.5n 18230
%96.8%90.9%
Mean4.12 ± 0.303.94 ± 0.36

Hyperuricemia (mg/dL)<7.2n 188
%9.6%24.2%
≥7.2n 17025
%90.4%75.8%
Mean8.19 ± 1.607.53 ± 2.05

Phosphate (mg/dL)<5.5n 5510
%29.3%30.3%
≥5.5n 13323
%70.7%69.7%
Mean6.48 ± 1.625.78 ± 1.45

Ca × P ([mg/dL]2)≥55n 12020
%63.8%60.6%
<55n 6813
%36.2%39.4%
Mean62.28 ± 16.6454.50 ± 14.03

Cholesterol (mg/dL)<200n 12022
%63.8%66.7%
≥200n 6811
%36.2%33.3%
Mean188.9 ± 46.2178.3 ± 32.0

Triglyceride (mg/dL)<150n 9620
%51.1%60.6%
≥150n 9213
%48.9%39.4%
Mean189.8 ± 190.4152.0 ± 91.5

iPTH (pg/mL)<2000n 18131
%96.3%93.9%
≥2000n 72
%3.7%6.1%
Mean1133.8 ± 391.61158.4 ± 372.8

CCI<5n 1089
%57.4%27.3%
≥5n 8024
%42.6%72.7%
Mean4.37 ± 1.885.52 ± 2.06

Intervention

ParathyroidectomyNon 13229
%70.2%87.9%
Yesn 564
%29.8%12.1%

CCI: Charlson comorbidity index.
Chi-square test.
test.