Parathyroidectomy Is Associated with Reduced Mortality in Hemodialysis Patients with Secondary Hyperparathyroidism

Table 2

Cox proportional hazard regression of overall survival analysis for 221 hemodialysis patients with iPTH over 800 pg/mL.

	Univariate regression model				Multivariate regression model ( = 218)
					Full model				Final model
	95.0% CI for HR				95.0% CI for aHR				95.0% CI for aHR
	HR	Lower	Upper	value	aHR	Lower	Upper	value	aHR	Lower	Upper	value
Age ≥65	3.31	1.63	6.72	0.001	2.43	1.08	5.50	0.033	2.11	1.01	4.38	0.046
Male gender	1.52	0.77	3.02	0.228	1.21	0.54	2.73	0.646
Hypertension	0.74	0.37	1.47	0.389	0.71	0.32	1.56	0.391
Diabetes mellitus	4.61	2.13	10.00	<0.001	2.74	1.17	6.40	0.020	3.80	1.73	8.37	0.001
Hb >10 g/dL	0.77	0.39	1.53	0.455	0.37	0.15	0.92	0.032
Albumin ≤3.5 g/dL	1.56	0.46	5.28	0.473	0.49	0.10	2.33	0.371
Hyperuricemia	0.43	0.19	0.95	0.038	0.47	0.19	1.17	0.104
Phosphate <5.5 mg/dL	1.22	0.58	2.57	0.595
Ca × P <55 (mg/dL)^2	1.56	0.77	3.14	0.217	1.11	0.50	2.44	0.799
Cholesterol ≥200 m/dL	0.87	0.42	1.80	0.699	1.34	0.52	3.48	0.546
Triglyceride ≥150 mg/dL	0.81	0.40	1.63	0.556	0.85	0.34	2.16	0.733
PTH ≥1500 pg/mL	0.89	0.31	2.53	0.825
PTH ≥2000 pg/mL	1.44	0.35	6.05	0.616	1.95	0.35	10.80	0.443
CCI ≥5	3.30	1.53	7.12	0.002	2.22	0.97	5.09	0.060
Parathyroidectomy	0.25	0.09	0.73	0.011	0.35	0.11	1.11	0.075	0.34	0.12	0.99	0.047