Research Article
Fuchs Endothelial Corneal Dystrophy: Strong Association with rs613872 Not Paralleled by Changes in Corneal Endothelial TCF4 mRNA Level
Table 1
Loci, genes, and genetic variants related to late-onset FECD.
| | Chromosome | Locus/gene/variant | Late-onset FECD |
| | 1p35.1 | rs760594 | F | | 5q12.3 | rs1301475 | F | | 5q33.1–q35.2 | FCD3 | F | | 7q22.3 | rs257376 | F | | 8p21.3 | rs2466216 | F | | 8p21.1 | rs9797 | F | | 8q21.13 | rs1380229 | F | | 9p22.1–p24.1 | FCD4 | F | | 10p11.22 | ZEB1 | F/S | | 10q24.2 | rs1889974 | F | | 13pter-q12.13 | FCD1 | F | | 15q22.2 | rs235512 | F | | 15q22.31 | rs352476 | F | | 15q25.3 | AGBL1 | F/S | | 17q25.3 | rs938350 | F | | 18q21.1 | LOXHD1 | F/S | | 18q21.2 | TCF4 | F/S | | 18q21.2–q21.32 | FCD2 | F | | 20p13 | SLC4A11 | F/S | | 20p12.2 | rs674630 | F | | Xq28 | rs1990383 | F |
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F: familial, S: sporadic.
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