Research Article
Protective Efficacy of an Inactive Vaccine Based on the LY02 Isolate against Acute Haemophilus parasuis Infection in Piglets
Table 4
Levels of various cytokines in the sera of piglets from each group.
| | Cytokine type | Group | Levels of each cytokine (means ± SD) at intervals (days) after the immunization | | 21 | 35 | 42 | 49 | 56 |
| | IL-2 | G1 | 104.5 ± 7.4 | 124.1 ± 19.5 | 116.1 ± 23.6 | 125.0 ± 15.5 | 113.5 ± 28.3 | | G2 | 122.2 ± 16.5 | 144.5 ± 22.4 | 111.3 ± 7.6 | 102.0 ± 19.6 | 101.2 ± 23.3 | | G3 | 105.7 ± 22.5 | 97.6 ± 23.5 | 90.3 ± 16.5 | 46.4 ± 19.5 | — |
| | IL-4 | G1 | 508.8 ± 52.0 | 540.1 ± 26.5 | 512.3 ± 66.0 | 661.5 ± 81.0 | 453.4 ± 68.4 | | G2 | 465.5 ± 40.3 | 508.0 ± 64.5 | 500.0 ± 22.3 | 445.5 ± 36.3 | 456.2 ± 114.9 | | G3 | 378.5 ± 10.4 | 428.0 ± 23.6 | 345.0 ± 52.1 | 191.8 ± 94.9 | — |
| | IL-10 | G1 | 408.3 ± 113.5 | 397.7 ± 106.7 | 413.8 ± 154.2 | 462.1 ± 123.5 | 423.3 ± 134.1 | | G2 | 376.5 ± 143.2 | 413.8 ± 118.8 | 409.1 ± 114.5 | 496.0 ± 103.5 | 483.5 ± 164.3 | | G3 | 352.6 ± 122.3 | 326.9 ± 159.6 | 299.7 ± 163.8 | 342.9 ± 145.2 | — |
| | TGF-β | G1 | 153.4 ± 50.2 | 173.5 ± 42.6 | 216.4 ± 30.8 | 197.5 ± 27.7 | 203.3 ± 30.4 | | G2 | 126.8 ± 34.6 | 168.7 ± 23.4 | 176.5 ± 32.4 | 183.6 ± 19.2 | 195.5 ± 27.5 | | G3 | 105.3 ± 53.4 | 96.2 ± 37.9 | 124.6 ± 34.8 | 116.8 ± 14.6 | — |
| | IFN-γ | G1 | 82.4 ± 24.3 | 123.5 ± 54.6 | 155.9 ± 12.9 | 187.6 ± 23.6 | 178.1 ± 20.5 | | G2 | 79.7 ± 13.8 | 103.2 ± 31.5 | 175.6 ± 31.9 | 189.8 ± 14.1 | 218.3 ± 27.1 | | G3 | 62.3 ± 15.6 | 58.7 ± 11.1 | 73.5 ± 20.9 | 65.1 ± 21.3 | — |
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, compared to G3.
compared to G2.
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