Screening Ingredients from Herbs against Pregnane X Receptor in the Study of Inductive Herb-Drug Interactions: Combining Pharmacophore and Docking-Based Rank Aggregation

Table 3

The top 10 of final rank for candidate agonist of PXR from herbal ingredients.

Rank	Ingredients	Herbs	Reference (Y/N)
1	Sophoraflavoside IV	Sophorae flavescentis	Y
2	Hesperidin	Sarothamnus scoparius	Y
		Scrophularia nodosa; Hyssopus officinalis; Tilia × europaea;Verbascum thapsus; Chlorella	N
3	Sennoside C&D	Cassia acutifolia	N
4	Ginsenosides Rgl	Astragalus membranaceus	Y
5	Chlorophy II	Medicago sativa; Urtica dioica	N
6	Solanine	Fritillariae cirrhosae	Y
7	Senegenic acid	Polygala senega	N
8	Sophoraflavoside III	Sophorae flavescentis	Y
9	Phellanmurin	Phellodendron amurense	Y
10	Torulosic acid	Juniperus communis	N