Systematic Analysis of the Associations between Adverse Drug Reactions and Pathways

Figure 4

Drug-ADR pairs interpreted by pathway categories. (a) For this given drug, two of three drug-ADR pairs can be interpreted by the identified ADR-pathway associations. If we concerned only one pathway category, then only a drug-ADR pair was interpreted. (b) The contributions of any pathway and each pathway category to ADRs were quantified. Only 284 ADRs in the AP network were investigated.

(a)

(b)