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BioMed Research International
Volume 2015, Article ID 671058, 7 pages
http://dx.doi.org/10.1155/2015/671058
Research Article

Analysis of Chemical Properties of Edible and Medicinal Ginger by Metabolomics Approach

1College of Pharmaceutical Science, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, Shiga 525-8577, Japan
2Center for Information Biology, National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan
3RIKEN Center for Sustainable Resource Science, Yokohama, Tsurumi 230-0045, Japan
4Department of Cancer Cell Biology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan
5Graduate School of Information Science, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan
6Faculty of Pharmaceutical Sciences, Hokuriku University, Ho-3 Kanagawa-machi, Kanazawa 920-1181, Japan

Received 27 April 2015; Revised 1 July 2015; Accepted 1 July 2015

Academic Editor: Paul M. Tulkens

Copyright © 2015 Ken Tanaka et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. WHO Media Centre, “Traditional medicine,” Fact Sheet 134, 2008, http://www.who.int/mediacentre/factsheets/fs134/en/. View at Google Scholar
  2. S. D. Ehrlich, Herbal Medicine, University of Maryland Medical Centre, 2010, http://www.umm.edu/altmed/articles/herbal-medicine-000351.htm.
  3. K. Tanaka, M. Arita, D. Li, N. Ono, Y. Tezuka, and S. Kanaya, “Metabolomic characterization of a low phytic acid and high anti-oxidative cultivar of turmeric,” Natural Product Communications, vol. 10, no. 2, pp. 329–334, 2015. View at Google Scholar
  4. D. Li, N. Ono, T. Sato et al., “Targeted integration of RNA-Seq and metabolite data to elucidate curcuminoid biosynthesis in four Curcuma species,” Plant and Cell Physiology, vol. 56, no. 5, pp. 843–851, 2015. View at Publisher · View at Google Scholar
  5. Y. Niu, F. Li, C. Inada et al., “Chemical profiling with HPLC-FTMS of exogenous and endogenous chemicals susceptible to the administration of chotosan in an animal model of type 2 diabetes-induced dementia,” Journal of Pharmaceutical and Biomedical Analysis, vol. 104, pp. 21–30, 2015. View at Publisher · View at Google Scholar · View at Scopus
  6. K. Tanaka, F. Li, Y. Tezuka, S. Watanabe, N. Kawahara, and H. Kida, “Evaluation of the quality of Chinese and Vietnamese cassia using LC-MS and multivariate analysis,” Natural Product Communications, vol. 8, no. 1, pp. 75–78, 2013. View at Google Scholar · View at Scopus
  7. P. N. Ravindran and K. Nirmal Babu, Ginger: The Genus Zingiber, CRC Press, 2004.
  8. A. Namera, Y. Yamamoto, and H. Khoda, “Quantitative analysis of zingerone and chromatographic fingerprint analysis of pungents and essential oils in processed ginger,” Shoyakugaku Zasshi, vol. 66, no. 1, pp. 17–22, 2012. View at Google Scholar
  9. H. Shimoda, S.-J. Shan, J. Tanaka et al., “Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents,” Journal of Medicinal Food, vol. 13, no. 1, pp. 156–162, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. http://www.hinsyu.maff.go.jp.
  11. L. Lv, H. Chen, D. Soroka, X. Chen, T. Leung, and S. Sang, “6-gingerdiols as the major metabolites of 6-gingerol in cancer cells and in mice and their cytotoxic effects on human cancer cells,” Journal of Agricultural and Food Chemistry, vol. 60, no. 45, pp. 11372–11377, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Kikuzaki, S.-M. Tsai, and N. Nakatani, “Gingerdiol related compounds from the rhizomes of Zingiber officinale,” Phytochemistry, vol. 31, no. 5, pp. 1783–1786, 1992. View at Publisher · View at Google Scholar · View at Scopus
  13. S. Dugasani, M. R. Pichika, V. D. Nadarajah, M. K. Balijepalli, S. Tandra, and J. N. Korlakunta, “Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol,” Journal of Ethnopharmacology, vol. 127, no. 2, pp. 515–520, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Tanabe, M. Yasuda, Y. Adachi, K. Ujita, and Y. Kano, “Growth of Japanese ‘Kintoki ginger‘ and contents of pungents and diterpenes,” Shoyakugaku Zasshi, vol. 46, no. 1, pp. 30–36, 1992. View at Google Scholar · View at Scopus
  15. S. Prasad and A. K. Tyagi, “Ginger and its constituents: role in prevention and treatment of gastrointestinal cancer,” Gastroenterology Research and Practice, vol. 2015, Article ID 142979, 11 pages, 2015. View at Publisher · View at Google Scholar
  16. A. H. Rahmani, F. M. Al Shabrmi, and S. M. Aly, “Active ingredients of ginger as potential candidates in the prevention and treatment of diseases via modulation of biological activities,” International Journal of Physiology, Pathophysiology and Pharmacology, vol. 6, no. 2, pp. 125–136, 2014. View at Google Scholar · View at Scopus
  17. S. Wang, C. Zhang, G. Yang, and Y. Yang, “Biological properties of 6-Gingerol: a brief review,” Natural Product Communications, vol. 9, no. 7, pp. 1027–1030, 2014. View at Google Scholar · View at Scopus
  18. D.-L. Lu, X.-Z. Li, F. Dai et al., “Influence of side chain structure changes on antioxidant potency of the [6]-gingerol related compounds,” Food Chemistry, vol. 165, pp. 191–197, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. N. Vijendra Kumar, P. S. Murthy, J. R. Manjunatha, and B. K. Bettadaiah, “Synthesis and quorum sensing inhibitory activity of key phenolic compounds of ginger and their derivatives,” Food Chemistry, vol. 159, pp. 451–457, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. H.-C. Shih, C.-Y. Chern, P.-C. Kuo et al., “Synthesis of analogues of gingerol and shogaol, the active pungent principles from the rhizomes of Zingiber officinale and evaluation of their anti-platelet aggregation effects,” International Journal of Molecular Sciences, vol. 15, no. 3, pp. 3926–3951, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. A. A. Rahman, S. Makpol, R. Jamal, R. Harun, N. Mokhtar, and W. Z. W. Ngah, “Tocotrienol-rich fraction, [6]-gingerol and epigallocatechin gallate inhibit proliferation and induce apoptosis of glioma cancer cells,” Molecules, vol. 19, no. 9, pp. 14528–14541, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Park, J. Bae, and D.-S. Lee, “Antibacterial activity of [10]-gingerol and [12]-gingerol isolated from ginger rhizome against periodontal bacteria,” Phytotherapy Research, vol. 22, no. 11, pp. 1446–1449, 2008. View at Publisher · View at Google Scholar · View at Scopus