Is Lipoprotein-Associated Phospholipase A2 a Link between Inflammation and Subclinical Atherosclerosis in Rheumatoid Arthritis?
Measurement of Lp-PLA2, intima media thickness (IMT), flow mediated dilatation (FMD), traditional risk factors for cardiovascular disease (CVD), and disease activity in patients with early rheumatoid arthritis (RA) and in age- and sex-matched controls evaluated both at baseline (T0) and after 5 years (T5). Data are expressed as mean value (standard deviation).
value < 0.05; value < 0.01; value < 0.0001; †p value = 0.061; all values compared with T0. Lp-PLA2: lipoprotein-associated phospholipase A2; HDL: high-density lipoproteins; BMI: body mass index; CRP: C-reactive protein; DAS28: disease activity score for 28-joint count.