Chitosan Prevents Gentamicin-Induced Nephrotoxicity via a Carbonyl Stress-Dependent Pathway

Figure 1

In vivo effects of LMWC on renal function in rats. Group C was the control group. Group G was treated with GM (150 mg/kg/day) for 6 days. Group Chil-G and Group Chih-G were treated with 165 and 825 mg/kg/day, respectively. Group met-G was treated with metformin. Serum creatinine, blood urea nitrogen, and microalbumin were altered in GN rats; however, these effects were reversed by LMWC. , compared to Group C; , compared to Group G. = 5-6.