Research Article

Chitosan Prevents Gentamicin-Induced Nephrotoxicity via a Carbonyl Stress-Dependent Pathway

Figure 3

Quantitative analysis of renal tissue lesions. The tubulointerstitial histological scores were determined for tubular necrosis atrophy (black bar) and cell infiltration (white bar). Group C was the control group. Group G was treated with GM (150 mg/kg/day) for 6 days. Groups Chil-G and Chih-G were GN rats treated with 165 and 825 LMWC mg/kg/day, respectively. Group met-G consisted of metformin-treated GN rats.