The Association between Serum LDL Cholesterol and Genetic Variation in Chromosomal Locus 1p13.3 among Coronary Artery Disease Patients
Table 1
(a) Clinical and biochemical data of cardiac patients. (b) Coronary artery disease risks factors among the study subjects.
(a)
Variables
Group (A)
Group (B)
value
Age (years)
56.86 (9.34)
56.33 (10.59)
0.701
BMI (kg/m2)
31.69 (6.19)
30.57 (6.94)
0.897
Body weight (kg)
81.85 (26.17)
80.49 (27.79)
SBP (mmHg)
129.73 (16.38)
132.95 (21.84)
0.290
DBP (mmHg)
72.42 (10.21)
72.83 (9.95)
0.790
Glucose (mM)
6.94 (5.47–8.41)
9.49 (8.15–10.83)
0.003
LDL (mM)
2.69 (2.42–2.96)
2.81 (2.59–3.01)
0.510
HDL (mM)
1.01 (0.94–1.11)
0.97 (0.92–1.04)
0.551
TC (mM)
4.61 (4.25–4.97)
4.70 (4.19–5.22)
0.728
TG (mM)
2.58 (1.45–3.07)
1.96 (1.71–2.21)
0.568
Troponin (ng/mL)
2.42 (0.01–4.29)
3.53 (1.01–7.87)
0.130
CK-MB (ng/mL)
7.68 (0.75–44.43)
34.53 (4.63–141.35)
0.082
Continuous data are presented as means (SD) for normally distributed data and mean and lower and upper 95%, CI. Categorical variables were presented as number and percent. BMI: body mass index, SBP: systolic blood pressure, DSB: diastolic blood pressure, TC: total cholesterol, TG: triglycerides, LDL-C: low-density lipoprotein cholesterol, HDL-C: high-density lipoprotein cholesterol, CK-MB: creatinine kinase MB protein. Two-tailed value is significant at <0.05.
(b)
Variables
Group A Nonsignificant stenosis
Group B Significant stenosis
value
CAD risk factors (, %)
(40%)
(60%)
Gender
Male
68.0 (74.7%)
110.0 (80.9%)
0.269
Female
23.0 (25.3%)
26.0 (19.1%)
Obesity
45.0 (49.5%)
71.0 (52.2%)
0.736
Hypertension (yes)
54.0 (59.3%)
84.0 (61.7%)
0.842
DM (yes)
40.0 (43.8%)
65.0 (62.5%)
0.008
Dyslipidemia (yes)
28.0 (33.73%)
41.0 (32.80%)
0.885
Smoking (yes)
30.0 (32.9%)
63.0 (46.3%)
0.062
FH of CAD (yes)
22.0 (24.1%)
40.0 (29.4%)
0.465
Use antidiabetic treatment
26.0 (28.6%)
40.0 (38.1%)
0.151
Use statin treatment
25.0 (34.2%)
38.0 (36.2%)
0.224
Categorical variables were presented as number and percent. DM: type 2 diabetes, FH of CAD: family history of coronary artery diseases. Two-tailed value is significant at <0.05.
