BioMed Research International / 2015 / Article / Tab 1

Research Article

Osteoarticular Expression of Musashi-1 in an Experimental Model of Arthritis

Table 1

Comparative study of morphological variables in DBA1/J mice after 21 and 28 days of starting treatment.

VariablesControl groupEtanercept group* valuesControl groupEtanercept group* values
Day 46 after immunizationDay 53 after immunization

Number of joints2.1 ± 0.691.8 ± 0.880.4122.45 ± 1.011.9 ± 0.560.006
Pannus1 ± 0.210.9 ± 0.350.4490.7 ± 0.311 ± 00.467
B & C injury1.8 ± 0.711.3 ± 0.780.2782 ± 0.941.55 ± 0.680.045
Inflammation1.5 ± 11.3 ± 10.6611.55 ± 0.831.1 ± 0.690.036
Bone marrow0.6 ± 0.470.5 ± 0.390.6130.55 ± 0.420.55 ± 0.430.930
Soft tissue0.15 ± 0.150.2 ± 0.210.5570.35 ± 0.310.15 ± 0.150.010

Mean score6.85 ± 2.955.8 ± 3.370.4698 ± 3.556 ± 2.120.011

Values are expressed as mean ± standard deviation; *treatment: etanercept 2 mg/week; B & C: bone and cartilage; Student’s -test. See Figure 3 for details.

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