Myeloperoxidase-Related Chlorination Activity Is Positively Associated with Circulating Ceruloplasmin in Chronic Heart Failure Patients: Relationship with Neurohormonal, Inflammatory, and Nutritional Parameters
Table 1
Clinical characteristics of heart failure patients and healthy Controls.
Controls ()
NYHA Class II ()
NYHA Class III ()
NYHA Class IV ()
Age, years
76 ± 11
76 ± 7
77 ± 10
75 ± 9
Gender, male
7
13
9
20
BMI (kg/m2)
23.7 ± 4.0
25.7 ± 2.9
23.8 ± 3.7
23.5 ± 3.6
Systolic BP (mm Hg)
135 ± 23
138 ± 19
136 ± 17
113 ± 19
Diastolic BP (mm Hg)
73 ± 8
80 ± 14
79 ± 12
64 ± 12†#
Heart rate (bpm)
81 ± 13
78 ± 11
72 ± 11
80 ± 11
Ischemia/hypertense/idiopathic
—
20/13/0
24/14/0
22/6/2
Current smoker (%)
47
35
14
35
Ejection fraction (%)
66 ± 6
51 ± 6
41 ± 7
29 ± 7
Haemoglobin (g/dL)
13.2 ± 1.0
12.9 ± 0.9
13.0 ± 1.4
12.6 ± 1.1
Neutrophils (103 cell/L)
2.70 ± 0.92
3.73 ± 1.43
3.51 ± 1.27
3.66 ± 1.21
Sodium (mEq/L)
141 ± 4
141 ± 4
138 ± 3
135 ± 5
eGFR (mL/min)
60 ± 22
49 ± 15
45 ± 18
41 ± 14
Data are reported as mean ± SD; eGFR: estimated glomerular filtration rate; indicates less than 0.05 versus Controls, † versus NYHA II, and # versus NYHA III.
