Research Article

High LIN28A Expressing Ovarian Cancer Cells Secrete Exosomes That Induce Invasion and Migration in HEK293 Cells

Figure 3

Detection of exosome-uptake by HEK293 cells. (a) HEK293 cells after exposure to CD63-GFP positive (green) and DiD-RFP labeled (red) IGROV1 secreted exosomes. 20x magnification was utilized to image HEK293 cells following exosome exposure using confocal microscopy. (b) Z-stack image of HEK293 cells after exposure to CD63-GFP positive (green) and DiD-RFP labeled (red) IGROV1 secreted exosomes. (c) Z-stack image of HEK293 cells after exposure to OV420 secreted, DiD labeled (red) exosomes. 40x magnification was utilized to image HEK293 cells following exosome exposure using confocal microscopy.
(a)
(b)
(c)