Assessing Age-Related Etiologic Heterogeneity in the Onset of Islet Autoimmunity

Table 2

Characteristics of DAISY subcohort by IA status ( = 359).

Characteristic	Number (%)		value
	Developed IA ( = 60)	Did not develop IA ( = 299)
Age, median (IQR), y	5.1 (6.3)^1	8.6 (6.3)^2	<0.0001
HLA-DR3/4, DQB1^*0302 genotype	21 (35%)	83 (28%)	0.26
First-degree relative with T1D	31 (52%)	118 (39%)	0.08
Female	35 (58%)	148 (50%)	0.21
Race/ethnicity, non-Hispanic white	47 (78%)	222 (74%)	0.51
Maternal age, mean (SD), y	30.5 (5.5)	30.0 (5.4)	0.47

DAISY, Diabetes Autoimmunity Study in the Young; HLA, human leukocyte antigen; IA, islet autoimmunity; T1D, type 1 diabetes.
¹Age at first IA positive visit.
²Age at last follow-up.