Research Article

Overexpression of GPC6 and TMEM132D in Early Stage Ovarian Cancer Correlates with CD8+ T-Lymphocyte Infiltration and Increased Patient Survival

Table 2

Survival characteristics of patients related to their tumoral GPC6 and TMEM132D mRNA levels.

AllGPC6 mRNA levelsTMEM132D mRNA levelsGPC6/TMEM132D mRNA levels
LowHighLowHighBoth lowHigh GPC6 and/or TMEM132D

N (%) 3528 (80)7 (20)26 (74.3)9 (25.7)22 (62.9)13 (37.1)
Survival
5-year survival (%)91.34 ± 4.7888.73 ± 6.1310088.29 ± 6.3610085.45 ± 7.78100
10-year survival (%)84.69 ± 6.3480.06 ± 8.0410078.73 ± 8.5510073.62 ± 10.27100
Overall survival (months)
Mean ± SE189 ± 12179 ± 15Undefineda152 ± 13Undefineda144 ± 15Undefineda
95% C.I.164–213149–209126–177114–174
Death cases (%)6 (17.14%)6 (21.4)0 (0)6 (23.1)0 (0)6 (27.3)0 (0)

value (log-rank test)0.2140.0990.032

aAll subjects alive.