Dendritic Cell-Based Immunotherapy Treatment for Glioblastoma Multiforme

Table 1

Comparison between GM-CSF and Flt3L in culturing DCs. GM-CSF: granulocyte macrophage colony-stimulating factor, Flt3L: FMS-like tyrosine kinase-3 ligand, DC: dendritic cell, DC1: type 1 polarizing DC, DC2: type 2 polarizing DC, Th1: helper T cell 1, and Th2: helper T cell 2.

	GM-CSF	Flt3L
DC subsets expending [17]	DC1 < DC2	DC1 > DC2
T cells expanding [17]		More memory CD4^+, CD8^+ T cells
Helper T cells expanding [17]	Both Th1 and Th2	Mainly Th1