Insulin Resistance-Associated Interhemispheric Functional Connectivity Alterations in T2DM: A Resting-State fMRI Study
Table 4
Regions showing significant differences in VMHC between patients and healthy controls.
Brain regions
MNI coordinates , , (mm)
Peak score
Voxels
Decreased in T2DM patients
Middle temporal gyrus
±54, −45, 6
−4.8383
289
Middle frontal gyrus
±45, 45, 24
−2.0195
100
Superior frontal gyrus
±15, 9, 57
−5.1613
267
Inferior parietal lobule
±63, −27, 21
−4.3842
97
Anterior cingulate gyrus
±6, 24, 21
−3.8309
91
Increased in T2DM patients
Inferior osccipital gyrus
±36, −72, −9
4.7328
199
Precentral gyrus
±36, −27, 63
3.2897
234
A corrected threshold of determined by Monte Carlo simulation was taken as meaning that there was a significant difference between groups. MNI: Montreal Neurological Institute; cluster size is in mm3.