Protective Effect of Enalapril against Methionine-Enriched Diet-Induced Hypertension: Role of Endoplasmic Reticulum and Oxidative Stress

Figure 5

Effect of MED and enalapril on ER stress in aortae of rats. Rats were fed SD or MED from 30th to 90th postnatal day with or without enalapril treatment from 60th to 90th postnatal day. After the experiment, phosphorylation of PERK (a) and eIF2α (b) and protein expression of ATF3 (c) and ATF6 (d) were determined by Western blot. Representative blot was shown. Results were also shown as means ± SEM. The bar graphs data resulted from the ratio of density of phosphorylated protein/total protein or target protein/corresponding protein. , compared with that of SD rats. , compared with that of MED rats.

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