BioMed Research International / 2015 / Article / Tab 3

Review Article

Fluid Therapy: Double-Edged Sword during Critical Care?

Table 3

Four phases of hemodynamic treatment.

RescueOptimizationStabilizationDeescalation

Treatment goalShock reversal/Life salvageAdequate tissue perfusionZero-to-negative daily fluid balanceFluid accumulation reversal/edema resolution

Time courseMinutesHoursDaysUp to weeks

Hemodynamic targetsAutoregulatory thresholds of perfusion pressureMicro/macrocirculatory blood flow parametersWeaning of vasopressors with stable hemodynamic conditionsReturn to premorbid/chronic values of pressure and flow

Treatment optionsRapid fluid boluses + vasopressorsRepeated fluid challenges + vasopressors + InotropesMaintenance fluids + decreasing/chronic vasoactive agentsDiuretics or other means of fluid removal