A Comparison of the Process of Remodeling of Hydroxyapatite/Poly-D/L-Lactide and Beta-Tricalcium Phosphate in a Loading Site

Figure 11

Tissue sections were stained for RUNX2 and viewed at ×100 and ×400 (insets) magnification. ((a), (c), and (e)) TCP group. ((b), (d), and (f)) HP group. ((a), (b)) 1 month. ((c), (d)) 3 months. ((e), (f)) 12 months. (g) The number of cells positive for RUNX2. β-TCP (grey box), HA/PDLLA (black box). Most of the spindle-shaped cells that were frequently observed in the HP group were positive for RUNX2. The HP group showed significantly more RUNX2-positive cells than did the TCP group during the follow-up period. In the HP group, specimens at 1 and 3 months demonstrated significantly more RUNX2-positive cells compared to the 12-month group. In the TCP group, the 3-month group demonstrated significantly more RUNX2-positive cells compared to the 1- and 12-month groups. : versus TCP group. †: versus 1 month. §: versus 3 months. Scale bars: 100 µm and 50 µm.