A Comparison of the Process of Remodeling of Hydroxyapatite/Poly-D/L-Lactide and Beta-Tricalcium Phosphate in a Loading Site

Figure 5

Tissue sections were stained with hematoxylin and eosin and viewed at ×12.5 and ×200 (insets) magnification. ((a), (c), and (e)) TCP group. ((b), (d), and (f)) HP group. ((a), (b)) 1 month. ((c), (d)) 3 months. ((e), (f)) 12 months. The HP group and TCP group showed the same level of bone formation. The HP group showed earlier scaffold resorption than did the TCP group. The process of remodeling was observed to be markedly different between the HP group and the TCP group. In particular, the HP group demonstrated significant fibrous tissue infiltration, whereas the TCP group did not. Scale bars: 1.0 mm and 100 µm.