Research Article

The Effect of Nicotine Dependence on Psychopathology in Patients with Schizophrenia

Table 1

Sociodemographic characteristics and clinical features according to nicotine dependence.

CharacteristicsNicotine dependenceNonnicotine dependenceStatisticOR/mean difference
(95% CI)

Age, years: mean (s.d.)39.6 (10.8)42.6 (11.6)0.087
Male, (%)68 (98.6)48 (42.9) <0.00190.6 (12.1–676)
Ethnicity, (%)
 Malay 41 (49.4)42 (37.5)
 Chinese20 (29)50 (44.6) <0.001
 Indian8 (11.6)20 (17.90)
Duration of illness, years: mean (s.d.)13.9 (10.4)15.6 (9.8)0.287
Atypical antipsychotic, (%)46 (66.7)53 (53.5)**0.0142.23 (1.19–4.15)
Chlorpromazine equivalents (mg), mean (s.d.)276.8 (190.6)291.1 (487.0)0.816
Taking illicit drugs/alcohol, (%)19 (27.5)2 (1.8) <0.010.05 (0.01–0.21)
Fagerstrom Test for Nicotine Dependencescore, mean (s.d.)4.16 (2.36)
CO ppm (s.d)13.91 (7.16)2.22 (0.65) <0.0111.69 (9.97–13.42)
Marital status, (%)
 Single50 (72.5)72 (64.3)0.22
 Divorced2 (2.9)1 (0.9)
 Married17 (24.6)39 (34.8)
Employment, (%)
 Employed41 (59.4)55 (49.1)0.22
 Unemployed28 (40.6)57 (50.9)
Total income, (%)
 ≤RM50043 (62.3)92 (82.1)*0.01411.35 (0.011–0.017)
 RM501–100015 (21.7)15 (13.4)
 RM1001–20006 (8.7)2 (1.8)
 RM2001–30004 (4.8)3 (2.7)
 >RM30001 (1.4)0
Education level, (%)
 Primary10 (14.5)15 (13.4)
 Secondary53 (76.8)75 (67)0.22
 College/university6 (8.7)21 (18.8)
 No education01 (0.9)

, , s.d. = standard deviation, OR = odds ratio, CI = confidence interval, and CO ppm = carbon monoxide in parts per million.