Research Article
Serum miR-224 Reflects Stage of Hepatocellular Carcinoma and Predicts Survival
Table 1
Patients’ characteristics.
| | Parameter | miR-224 low
() | miR224 high
() | value |
| | Age, years, mean ± SD | 54 ± 11.8 | 52.5 ± 9.3 | 0.366 | | Gender (male/female) | 69/22 | 86/5 | 0.001 | | Hepatitis B, (%) | 74 (81.3) | 85 (93.4) | 0.015 | | TBIL (umol/L) | 17.1 ± 8.8 | 19.1 ± 12.7 | 0.103 | | DBIL (umol/L) | 5.7 ± 3.4 | 7.9 ± 7.2 | 0.022 | | ALT (IU/L) | 34.6 ± 20.9 | 59.4 ± 65.9 | 0.000 | | AST (IU/L) | 40.2 ± 23.8 | 80.5 ± 81.9 | 0.000 | | γ-GGT (IU/L) | 126.5 ± 151.7 | 215.5 ± 223.1 | 0.000 | | LDH (IU/L) | 198.9 ± 88.9 | 286.7 ± 177.4 | 0.000 | | ALP (IU/L) | 122.1 ± 86.2 | 167 ± 126.7 | 0.000 | | ALB (g/L) | 40.1 ± 4.8 | 38.2 ± 4.6 | 0.007 | | PT (s) | 12.6 ± 0.96 | 12.9 ± 1.04 | 0.011 | | INR | 1.07 ± 0.08 | 1.09 ± 0.09 | 0.018 | | Child-Pugh (A/B) | 87/4 | 76/15 | 0.03 | | BCLC (B/C) | 58/33 | 40/51 | 0.012 | | AFP (ng/mL) | 1049 ± 1442 | 1822 ± 1702 | 0.001 |
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TBIL: total bilirubin; D-TBIL: direct bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; -GGT: -glutamyl transferase; LDH: lactic dehydrogenase; ALP: alkaline phosphatase; ALB: albumin; PT: prothrombin time activity percentage; INR: international normalized ratio.
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