Similarities in Gene Expression Profiles during In Vitro Aging of Primary Human Embryonic Lung and Foreskin Fibroblasts

Figure 7

Combined line plot showing the scaled and clustered expression profiles of 1,803 genes detected in both cell lines as differentially expressed. The middle line, including the points, indicates the mean expression profile for all included genes in a certain cluster. The thicker lines above and below indicate the standard deviation. Cell lines are indicated by color (green lines: MRC-5; red lines: HFF cells). The horizontal dotted green lines can be used to compare the mean profiles of both cell lines. The last plot shows a summary of the cluster validation analysis. An optimal number of five clusters were estimated.