Research Article

Use of Contrast-Enhanced Ultrasound to Study Relationship between Serum Uric Acid and Renal Microvascular Perfusion in Diabetic Kidney Disease

Table 2

Ultrasound parameters in the different study groups.

ParametersNormal control (NC)Diabetic kidney disease (DKD)
Normal SUAHigh SUA

Number263629
IMAX (%)
RT (s)
TTP (s)22.27 (15.4–31.0)19.74 (15.2–26.2)21.36 (16.6–28.6)
mTT (s)
AUC
AUC11795 (1439–2257)*1148 (981.8–13961411 (1056–1792
AUC2

Values are represented as mean ± standard error. SUA, serum uric acid. SUA ≥360 μmol/L (6 mg/dL) in females and ≥420 μmol/L (7 mg/dL) in males are considered as high SUA; otherwise, they are considered as normal SUA. , compared to DKD patients with normal SUA; , compared to normal control. Ultrasound parameters abbreviations used are as follows: IMAX, maximum intensity; RT, rise time; TTP, time to peak; mTT, mean transit time; AUC, the area under the perfusion curve; AUC1, area under the ascending curve; AUC2, area under the descending curve.