Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway

Figure 1

Viability analysis of BMDM cells after treatment with AGEs. Cells (5 × 10⁴/well) were treated with AGEs (20–500 μg/mL) for 24 h or with 500 μg/mL BSA as controls. Cell viability was determined by CCK-8 assay. Compared with BSA, AGEs (20–500 μg/mL) did not affect macrophages viability. Each bar represents the mean value ± SD of triplicate determinations, representative of three independent experiments.