Plant Antimicrobial Peptides as Potential Anticancer Agents

Table 3

Plant defensins with anticancer and cytotoxic activity.

Name	Species	Activity against	Cytotoxic activity	Anticancer activity	Reference
Sesquin	Vigna sesquipedalis	MCF-7 and M1	Not tested	Yes	[44]
Limenin	Phaseolus limensis	L1210 and M1	Not tested	Yes	[41]
Lunatusin	Phaseolus lunatus	MCF-7; rabbit reticulocyte	Yes	Yes	[45]
Purple pole defensin	Phaseolus vulgaris cv. “Extra-long Purple Pole bean”	HepG2, MCF7, HT-29, and SiHa	No	Yes	[46]
Coccinin	Phaseolus coccineus cv. “Major”	HL60 and L1210	No	Yes	[47]
Phaseococcin	Phaseolus coccineus	L1210 and HL60	No	Yes	[48]
-Thionin	Capsicum chinense	HeLa	No	Yes	[49]
NaD1	Nicotiana alata	U937	Not tested	Yes	[67]
Mitogenic defensin	Phaseolus vulgaris	MCF-7, murine splenocytes	Yes	Yes	[68]
Vulgarinin	Phaseolus vulgaris	MCF-7, L1210, and M1	Not tested	Yes	[69]
Cloud bean defensin	Phaseolus vulgaris cv. cloud bean	L1210 and MBL2	Not tested	Yes	[70]
Nepalese	Phaseolus angularis	L1210, MBL2	Not tested	Yes	[71]
Gymnin	Gymnocladus chinensis Baill	M1, HepG2, and L1210	Not tested	Yes	[72]