Plant Antimicrobial Peptides as Potential Anticancer Agents

Table 4

Cyclotides with anticancer and cytotoxic activity.

Name	Species	Activity against	Cytotoxic activity	Anticancer activity	Reference
Cycloviolacin O2	Viola odorata	U-937, HeLa	Yes	Yes	[54]
Viphi A, Viphi F, and Viphi G	Viola philippica	MM96L, HeLa, BGC-823, and HFF-1	Yes	Yes	[51]
MCoTI-I	Momordica cochinchinensis	LNCaP and HCT116	Not tested	Yes	[81]
HB7	Hedyotis biflora	Capan2 and PANC1	Not tested	Yes	[82]
Vaby A and Vaby D	Viola abyssinica	U-937	Not tested	Yes	[83]
Cliotides T1–T4	Clitoria ternatea	HeLa and human erythrocytes	Yes	Yes	[84]
Psyle A, Psyle C, and Psyle E	Psychotria leptothyrsa	U-937	Not tested	Yes	[85]
Vibi G and Vibi H	Viola biflora	U-937	Not tested	Yes	[86]
Varv A and Varv F	Viola arvensis	10 cancer cell lines	Not tested	Yes	[87]
Viba 15, Viba 17, and Mram 8	Viola philippica	HFF1, MM96L, HeLa, BGC-823, and HFF-1	Yes	Yes	[51]
CT-2, CT-4, CT-7, CT-10, CT-12, and CT-19	Clitoria ternatea	A549	Not tested	Yes	[88]
Kalata B1 and kalata B2	Oldenlandia  affinis	U-937 GTB; HT-29; Ht116	Yes	Yes	[89]