The Evolving Genotypic Profile of HIV-1 Mutations Related to Antiretroviral Treatment in the North Region of Brazil

Table 1

Characteristics of patients failing ARV.

Characteristics	Total (377)
Age in years
Mean (range)	40.73 (±9.43)
Gender
Male	250 (66.3%)
CD4+ count (cells/µL)
Mean (range)	199.93 (±173,36)
HIV RNA level
Mean (range)	5.005 (±5,509)
Number of therapeutic failures
First treatment	91 (24.2%)
Second treatment	85 (22.5%)
Multiexperienced	201 (53.3%)
ARVs before genotyping
NRTIs + NNRTIs	177 (46.9%)
NRTIs + PI/r	131 (34.8%)
NRTIs + PI	53 (14.1%)
NRTIs + NNRTIs + PI/r	12 (3.2%)
NRTIs + double-boosted PI	2 (0.5%)
NRTIs only	2 (0.5%)

Antiretrovirals, ARV; nucleoside reverse transcriptase inhibitors, NRTIs; nonnucleoside reverse transcriptase inhibitors, NNRTIs; protease inhibitors, PI; boosted protease inhibitors, PI/r.