SAMHD1 Gene Mutations Are Associated with Cerebral Large-Artery Atherosclerosis
Radiologic findings of the cerebral large arteries in 3 patients with SAMHD1 gene mutations. In each panel (a–c) the abnormal neuroimaging findings (upper) and sequence electropherogram with the identified SAMHD1 mutation (lower) are shown. The imaging examination was performed with either contrast-enhanced magnetic resonance angiography (a) or magnetic resonance angiography (b and c). Orange-coloured arrows indicate stenoses of the large arteries and black arrows show the mutations of the SAMHD1 gene.