Table 3: Receiver-operating characteristic analysis of methylated genes for diagnosis of GC.

GeneNumber of controls/CAG samples without DNA methylation detected/total number of controls/CAG samples (%)Number of GC samples with DNA methylation detected/total number of GC samples (%)SpecificitySensitivityAUC (SE)95% CI

FLNC80/86 (93.0)55/82 (67.1)93.067.10.718 (0.037)0.65–0.79
THBS181/86 (94.2)52/82 (63.4)94.263.40.706 (0.038)0.63–0.78
UCHL177/86 (89.5)46/82 (56.1)89.556.10.663 (0.041)0.60–0.73
DLEC180/86 (93.0)66/82 (80.5)93.080.50.868 (0.033)0.80–0.91

GC, gastric cancer; CAG, chronic atrophic gastritis; AUC, area under the curve; SE, standard error; CI, confidence internal.