The Diagnosis Value of Promoter Methylation of UCHL1 in the Serum for Progression of Gastric Cancer

Table 3

Receiver-operating characteristic analysis of methylated genes for diagnosis of GC.

Gene	Number of controls/CAG samples without DNA methylation detected/total number of controls/CAG samples (%)	Number of GC samples with DNA methylation detected/total number of GC samples (%)	Specificity	Sensitivity	AUC (SE)	95% CI
FLNC	80/86 (93.0)	55/82 (67.1)	93.0	67.1	0.718 (0.037)	0.65–0.79
THBS1	81/86 (94.2)	52/82 (63.4)	94.2	63.4	0.706 (0.038)	0.63–0.78
UCHL1	77/86 (89.5)	46/82 (56.1)	89.5	56.1	0.663 (0.041)	0.60–0.73
DLEC1	80/86 (93.0)	66/82 (80.5)	93.0	80.5	0.868 (0.033)	0.80–0.91

GC, gastric cancer; CAG, chronic atrophic gastritis; AUC, area under the curve; SE, standard error; CI, confidence internal.