Phytochemical Screening and Acute Oral Toxicity Study of Java Tea Leaf Extracts
Table 4
Effect of OS extracts on relative organ weights in rats during 14-day oral acute toxicity study.
CON
OSA
OSF
OSE
Male
Liver
4.83 ± 0.10
4.72 ± 0.19
4.83 ± 0.26
5.43 ± 0.19
Kidney (R)
0.77 ± 0.01
0.72 ± 0.01
0.73 ± 0.04
0.78 ± 0.04
Kidney (L)
0.75 ± 0.01
0.73 ± 0.01
0.74 ± 0.03
0.70 ± 0.02
Stomach
0.99 ± 0.03
0.91 ± 0.03
0.90 ± 0.02
1.02 ± 0.05
Testis
0.86 ± 0.02
0.84 ± 0.04
0.85 ± 0.04
0.84 ± 0.03
Female
Liver
3.99 ± 0.16
4.59 ± 0.13
4.56 ± 0.28
4.75 ± 0.29
Kidney (R)
0.78 ± 0.01
0.80 ± 0.01
0.81 ± 0.03
0.83 ± 0.03
Kidney (L)
0.75 ± 0.01
0.75 ± 0.02
0.78 ± 0.02
0.80 ± 0.03
Stomach
1.05 ± 0.03
1.03 ± 0.03
0.96 ± 0.04
1.01 ± 0.09
Ovary
0.44 ± 0.01
0.53 ± 0.08
0.43 ± 0.01
0.45 ± 0.03
Data are expressed as mean ± standard error of the mean (SEM) and analyzed by one-way ANOVA, followed by Dunnett’s test () as compared to respective parameter value of control groups (CON: 6 males and 6 females).