Expression of Adiponectin Receptors on Peripheral Blood Leukocytes of Hypertensive Children Is Associated with the Severity of Hypertension
Table 1
Comparison of demographic, anthropometric, and laboratory data in control group and AdipoR(+) and AdipoR(−) group of hypertensive children.
Variables
Control ()
Group of hypertensive children
AdipoR(+) ()
AdipoR(−) ()
Value AdipoR(+) versus AdipoR(−)
Age (years)
13.9 ± 3.5
15.0 ± 2.6
15.0 ± 2.6
0.964
Growth, cm
157.8 ± 22.9
170.7 ± 14.8†
167 ± 13.8
0.383
Weight, kg
55.1 ± 21.8
75.5 ± 17.9†
72.5 ± 20.5‡
0.570
BMI
21.0 ± 4.3
25.6 ± 4.3†
25.5 ± 4.6‡
0.896
BMI-SDS
0.5 ± 1.0
1.3 ± 0.8†
1.3 ± 0.9‡
0.942
Waist circumference, cm
68.8 ± 8.5
82.7 ± 8.3†
83.6 ± 12.9‡
0.782
Waist circumference SDS
0.7 ± 0.6
1.4 ± 0.7
1.3 ± 1.1
0.690
24 h SBP, mm Hg
110.3 ± 14.4
130.5 ± 8.7†
125 ± 9.4‡
0.042*
24 h DBP, mm Hg
62.7 ± 5.5
73.0 ± 5.7†
71.1 ± 6.1‡
0.225
24 h MAP, mm Hg
88.6 ± 9.8
92.3 ± 5.9
89.4 ± 5.9
0.073
24 h heart rate, beats/min
75.1 ± 13.8
78.0 ± 14.1
79.1 ± 13.4
0.740
Left ventricular mass index, g/m2.7
28.2 ± 5.8
32.7 ± 6.5
34.5 ± 8.9
0.383
Carotid intima-media thickness, m
0.42 ± 0.03
0.45 ± 0.04
0.42 ± 0.04
0.017*
Carotid intima-media thickness -score
0.7 ± 0.7
1.57 ± 1.2
1.04 ± 1.0
0.073
Carotid wall cross-sectional area, mm2
6.8 ± 0.9
8.0 ± 1.5†
7.5 ± 1.4
0.092
Total cholesterol, mg/DL
178.6 ± 28.3
171.8 ± 35.1
174.5 ± 30.3
0.760
HDL cholesterol, mg/dL
53.4 ± 19.8
50.9 ± 13.9
51.4 ± 13.8
0.890
LDL cholesterol, mg/dL
109.0 ± 24.7
96.7 ± 29.4
101.9 ± 25.0
0.471
Triglycerides, mg/dL
85.9 ± 42.0
127.2 ± 79.3
111.7 ± 50.5
0.389
Uric acid mg/dL
5.1 ± 0.9
6.0 ± 1.4
5.8 ± 1.2
0.457
hsCRP, mg/L
0.2 ± 0.08
0.32 ± 0.2
0.28 ± 0.1
0.488
sCD14 ng/mL
998.5 ± 152.3
779.4 ± 174.1†
885.4 ± 304.1
0.008*
Results presented as mean ± SD. BMI indicates body mass index; DBP, diastolic blood pressure; HDL, high-density lipoprotein, hsCRP, high sensitivity C-reactive protein; LDL, low-density lipoprotein; MAP, mean arterial pressure; SBP, systolic blood pressure. Statistically significant differences are given as follows: *AdipoR(+) versus AdipoR(−), †AdipoR(+) versus control, ‡AdipoR(−) versus control, is considered significant.